Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin (Q44170594)

30 November 2017

Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin (English)

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30 November 2017

5

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30 November 2017

Beom Seok Kim

1

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30 November 2017

T Ashton Cropp

series ordinal

2

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30 November 2017

Brian J Beck

series ordinal

3

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30 November 2017

David H Sherman

series ordinal

4

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30 November 2017

language of work or name

English

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publication date

3 October 2002

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Journal of Biological Chemistry

30 November 2017

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30 November 2017

277

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30 November 2017

50

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30 November 2017

48028-48034

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Genetic Contributions to Understanding Polyketide Synthases

30 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M207770200

Molecular genetics of polyketides and its comparison to fatty acid biosynthesis

21 January 2018

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Polyketide synthesis: prospects for hybrid antibiotics

21 January 2018

1 reference

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Modular organization of genes required for complex polyketide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207770200

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Expression in Escherichia coli, purification and characterization of two mammalian thioesterases involved in fatty acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

A new enzyme superfamily - the phosphopantetheinyl transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Substrate specificity of the loading didomain of the erythromycin polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Mechanisms of molecular recognition in the pikromycin polyketide synthase

21 January 2018

1 reference

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Conversion of a beta-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Engineered fatty acid biosynthesis in Streptomyces by altered catalytic function of beta-ketoacyl-acyl carrier protein synthase III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Type II thioesterase from Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Alternative modular polyketide synthase expression controls macrolactone structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Genetic evidence for a role of thioesterase domains, integrated in or associated with peptide synthetases, in non-ribosomal peptide biosynthesis in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

The thioesterase of the erythromycin-producing polyketide synthase: mechanistic studies in vitro to investigate its mode of action and substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Thioesterases and the premature termination of polyketide chain elongation in rifamycin B biosynthesis by Amycolatopsis mediterranei S699

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

A chain initiation factor common to both modular and aromatic polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

Heterogeneity of mouse satellite DNA on silver-cesium sulphate density gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207770200

21 January 2018

Identifiers

DOI

10.1074/JBC.M207770200

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30 November 2017

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