Developing a new resource for drug discovery: marine actinomycete bacteria (Q43415262)

23 November 2017

Developing a new resource for drug discovery: marine actinomycete bacteria (English)

1 reference

23 November 2017

0 references

1 reference

1

William Fenical

1 reference

23 November 2017

Paul R Jensen

2

1 reference

23 November 2017

1 December 2006

1 reference

23 November 2017

Nature Chemical Biology

1 reference

23 November 2017

2

1 reference

23 November 2017

12

1 reference

23 November 2017

666-673

1 reference

https://scigraph.springernature.com/pub.10.1038/nchembio841

23 November 2017

0 references

cites work

Natural products as sources of new drugs over the period 1981-2002.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

The evolving role of natural products in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Lessons from natural molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Environmental genome shotgun sequencing of the Sargasso Sea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Discovery of novel metabolites from marine actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Bioactive microbial metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Diversity of actinomycetes isolated from Challenger Deep sediment (10,898 m) from the Mariana Trench.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Widespread and persistent populations of a major new marine actinomycete taxon in ocean sediments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Structure-activity relationship studies of salinosporamide A (NPI-0052), a novel marine derived proteasome inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

A simple stereocontrolled synthesis of salinosporamide A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Total synthesis of salinosporamide A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Sporolides A and B: structurally unprecedented halogenated macrolides from the marine actinomycete Salinispora tropica.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Biogeography of the marine actinomycete Salinispora

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Lomaiviticins A and B, potent antitumor antibiotics from Micromonospora lomaivitiensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Diazepinomicin, a new antimicrobial alkaloid from a marine Micromonospora sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Cyanosporasides A and B, chloro- and cyano-cyclopenta[a]indene glycosides from the marine actinomycete "Salinispora pacifica".

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Phenotypic taxonomy and metabolite profiling in microbial drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Diversity and biogeography of marine actinobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

The crisis in antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Antibiotic terpenoid chloro-dihydroquinones from a new marine actinomycete

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Vanadium haloperoxidase-catalyzed bromination and cyclization of terpenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Isolation and characterization of novel marine-derived actinomycete taxa rich in bioactive metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Marine actinomycetes as a source of novel secondary metabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Marine natural products and related compounds in clinical and advanced preclinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Statistical approaches for estimating actinobacterial diversity in marine sediments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Biosynthesis of polyketides in heterologous hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Improved culturability of soil bacteria and isolation in pure culture of novel members of the divisions Acidobacteria, Actinobacteria, Proteobacteria, and Verrucomicrobia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Actinomycetes in North Sea and Atlantic Ocean Sediments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Marinomycins A-D, antitumor-antibiotics of a new structure class from a marine actinomycete of the recently discovered genus "marinispora".

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

Where will new antibiotics come from?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Rhodococcus marinonascens sp. nov., an Actinomycete from the Sea

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Salinibacterium amurskyense gen. nov., sp. nov., a novel genus of the family Microbacteriaceae from the marine environment

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Serinicoccus marinus gen. nov., sp. nov., a novel actinomycete with L-ornithine and L-serine in the peptidoglycan

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Distribution of actinomycetes in near-shore tropical marine sediments

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

A concise total synthesis of salinosporamide A

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Cyclomarins A−C, New Antiinflammatory Cyclic Peptides Produced by a Marine Bacterium (Streptomycessp.)

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

The structure of roflamycoin, a new polyene macrolide antifungal antibiotic

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Marinone and debromomarinone: Antibiotic sesquiterpenoid naphthoquinones of a new structure class from a marine bacterium

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Combinatorial biosynthesis of antibiotics: challenges and opportunities

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide synthetase

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO841

7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO841

1 reference

23 November 2017

1 reference

PubMed ID

17108984